Dresden University of Technology invites application for vacant (92) PhD, Postdoc and Research Positions
https://scholaridea.com/2024/06/29/dresden-university-of-technology-invites-application-for-vacant-92-phd-postdoc-and-research-positions/
https://scholaridea.com/2024/06/29/dresden-university-of-technology-invites-application-for-vacant-92-phd-postdoc-and-research-positions/
27/06/2024
BBC Radio 4
Can fortified drinks and spreads really reduce cholesterol?
Almost half of UK adults have raised cholesterol, according to the charity Heart UK - and Sliced Bread listener Cathy is one of them. She found out after taking a test at her GP and wants to do something about it. Her first plan of action is to make changes to her lifestyle, such as diet and exercise. As part of that, Cathy wants to know if the spreads and drinks that claim to lower cholesterol really do work.
Greg Foot is joined by Cathy and a panel of experts at our studios in Salford to investigate. What are the ingredients that are proven to lower cholesterol? How effective are they compared to widely-prescribed statins - and are the supermarket own brand versions of these drinks and spreads just as good as branded ones?
Almost half of UK adults have raised cholesterol, according to the charity Heart UK - and Sliced Bread listener Cathy is one of them. She found out after taking a test at her GP and wants to do something about it. Her first plan of action is to make changes to her lifestyle, such as diet and exercise. As part of that, Cathy wants to know if the spreads and drinks that claim to lower cholesterol really do work.
Greg Foot is joined by Cathy and a panel of experts at our studios in Salford to investigate. What are the ingredients that are proven to lower cholesterol? How effective are they compared to widely-prescribed statins - and are the supermarket own brand versions of these drinks and spreads just as good as branded ones?
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Milliy Universiteti Fizika fakultetida 2-yil dars berdim. Dars berish davomida salohiyatli kadrlarni tanlab loyihalarga (Center for Advanced Technologies - CAT Ilg'or texnologiyalar markazi - ITM) ishga oldim. 2 yil davomida yaxshi ishlashdi va 4 kursni tamomlagan bakalavrlarimiz Javokhir Khursandov, Rasul Mashalov hamda magistr talabamiz Muhriddindan Q1 jurnalda maqolamiz bugun online paydo boβldi. Shogirdlarimiz baraka topsin astoydil harakat qilishyapti. Maqolada ishtirok etgan hamkasblar Avez Sharipov hamda Farxod Turgunboyevga o'z minnatdorchiligimni bildiraman. Maqola haqida ma'lumot:
π§ π Parkinson kasalligi (PD) - bu hozirda to'liq va aniq davolash strategiyalari yetishmayotgan neyrodejenerativ kasalliklar toifasi. PDning kelib chiqishi Ξ±-sinuklein deb nomlanuvchi peptidlarni aggregatsiyasi bilan bogβliq. Tashqi elektrostatik maydon qo'llanishi natijasida tolali strukturalarning peptidlarga ajralishi mumkinligi kuzatildi π§¬π‘
Ushbu hodisani tushunish uchun biz molekulyar dinamika (MD) simulyatsiya usullaridan foydalanib, 0.1 V/nm elektr maydoni ta'sirida Ξ±-sinuklein peptidlarini o'rganib chiqdik. π¬β‘οΈ MD simulyatsiyalari natijalari shuni ko'rsatdiki, tashqi elektr maydoni ta'sirida Ξ±-sinuklein monomer va oligomerik shakllari sezilarli konformatsion o'zgarishlarga uchrab, ularning qayta yig'ilishiga to'sqinlik qiladi. Biroq, model tizimdagi peptid birliklari soni oshgan sari, trimer va tetramerlar hosil bo'lganida, elektr maydoniga nisbatan barqarorlik ham oshadi. ππ¬
Bizning natijalarimiz shuni ko'rsatadiki, erta tashxis bilan PD rivojlanishini oldini olishda muhim bo'lishi mumkin. Ξ±-sinuklein asosan monomer yoki dimer shaklida mavjud bo'lganida, hatto elektr maydoni kichik qiymatlarini qo'llash ham dastlabki yig'ilish jarayonini samarali ravishda buzishi mumkin. β³π
Ξ±-sinuklein fibril shakllanishini erta bosqichlarda to'xtatish PDni kuchayib borayotgan va patogen Ξ±-sinuklein fibrillarining hosil bo'lishini to'xtatish orqali kurashishning samarali yechimi bo'lishi mumkin. ππ§¬π‘
π§ π Parkinson kasalligi (PD) - bu hozirda to'liq va aniq davolash strategiyalari yetishmayotgan neyrodejenerativ kasalliklar toifasi. PDning kelib chiqishi Ξ±-sinuklein deb nomlanuvchi peptidlarni aggregatsiyasi bilan bogβliq. Tashqi elektrostatik maydon qo'llanishi natijasida tolali strukturalarning peptidlarga ajralishi mumkinligi kuzatildi π§¬π‘
Ushbu hodisani tushunish uchun biz molekulyar dinamika (MD) simulyatsiya usullaridan foydalanib, 0.1 V/nm elektr maydoni ta'sirida Ξ±-sinuklein peptidlarini o'rganib chiqdik. π¬β‘οΈ MD simulyatsiyalari natijalari shuni ko'rsatdiki, tashqi elektr maydoni ta'sirida Ξ±-sinuklein monomer va oligomerik shakllari sezilarli konformatsion o'zgarishlarga uchrab, ularning qayta yig'ilishiga to'sqinlik qiladi. Biroq, model tizimdagi peptid birliklari soni oshgan sari, trimer va tetramerlar hosil bo'lganida, elektr maydoniga nisbatan barqarorlik ham oshadi. ππ¬
Bizning natijalarimiz shuni ko'rsatadiki, erta tashxis bilan PD rivojlanishini oldini olishda muhim bo'lishi mumkin. Ξ±-sinuklein asosan monomer yoki dimer shaklida mavjud bo'lganida, hatto elektr maydoni kichik qiymatlarini qo'llash ham dastlabki yig'ilish jarayonini samarali ravishda buzishi mumkin. β³π
Ξ±-sinuklein fibril shakllanishini erta bosqichlarda to'xtatish PDni kuchayib borayotgan va patogen Ξ±-sinuklein fibrillarining hosil bo'lishini to'xtatish orqali kurashishning samarali yechimi bo'lishi mumkin. ππ§¬π‘
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Ξ±-sinuklein fibril shakllanishini erta bosqichlarda to'xtatish PDni kuchayib borayotgan va patogen Ξ±-sinuklein fibrillarining hosil bo'lishini to'xtatish orqali kurashishning samarali yechimi bo'lishi mumkin. ππ§¬π‘ https://www.sciencedirect.com/science/article/abs/pii/S1047847724000492
#ParkinsonsDisease #NeurodegenerativeDisorders #MolecularDynamics #Research #AlphaSynuclein #ElectricField #EarlyIntervention #ScientificDiscovery #HealthInnovation #BiomedicalResearch
#ParkinsonsDisease #NeurodegenerativeDisorders #MolecularDynamics #Research #AlphaSynuclein #ElectricField #EarlyIntervention #ScientificDiscovery #HealthInnovation #BiomedicalResearch
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π Bugun institutimizga TIQXMMI Milliy Tadqiqot Universiteti rektori Prof. Bakhadir Mirzaev tashrif buyurdi. Institut jamoasi bilan uchrashuv davomida hozirgi yutuqlarimizni hamda kelajakdagi rejalarni muhokama qildik. Katta muvaffaqiyatga erishish va keyingi rivojlanish strategiyalarini belgilash bo'yicha oβz maslahatlari bilan boβlishdilar. π
π Uchrashuv davomida meni Fundamental va Amaliy Tadqiqotlar Instituti direktori etib tayinladilar. Albatta bu katta mas'uliyat. Nasib bo'lsa institut jamoasi bilan birgalikda mamlakatimizning rivojlanishiga katta hissa qo'shadigan ajoyib natijalarga erishishimizga ishonaman ππ
π Uchrashuv davomida meni Fundamental va Amaliy Tadqiqotlar Instituti direktori etib tayinladilar. Albatta bu katta mas'uliyat. Nasib bo'lsa institut jamoasi bilan birgalikda mamlakatimizning rivojlanishiga katta hissa qo'shadigan ajoyib natijalarga erishishimizga ishonaman ππ
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Memorandum of Understanding (MoU) Signed Between IFAR and CAT
We are pleased to announce that the Institute of Fundamental and Applied Research (IFAR) at the National Research University TIIAME, represented by its Director, Dr. Jamoliddin Razzokov, has signed a Memorandum of Understanding (MoU) with the Center for Advanced Technologies (CAT) under the Ministry of Higher Education, Science and Innovation, represented by its deputy Director, Dr. Dilbar Dalimova.
This MoU marks the beginning of a collaborative partnership aimed at advancing research in several critical areas, including:
- Plasma Medicine: Leveraging non-thermal plasma (NTP) for cancer treatment through a combination of computer simulations and experimental studies to understand its selective effects on cancer cells.
- Neurological Diseases: Addressing the complexities of diseases such as Parkinson's and Alzheimer's by exploring the impact of electric fields and drugs on amyloid fibers using a blend of in-vitro experiments and computer simulations.
- Artificial Intelligence: Utilizing AI to identify peptide-based inhibitors for proteins involved in various diseases.
- Chronic Wound Healing: Investigating the potential of NTP to accelerate wound healing through combined in-vivo and in-silico studies.
Both IFAR and CAT are committed to sharing resources, expertise, and information to achieve these objectives, with plans for regular meetings, joint publications, and presentations at scientific conferences. This collaboration aims to develop innovative solutions and standards for medical treatments, benefiting the scientific community and patients alike.
We look forward to the groundbreaking research and advancements that will emerge from this partnership over the next five years.
We are pleased to announce that the Institute of Fundamental and Applied Research (IFAR) at the National Research University TIIAME, represented by its Director, Dr. Jamoliddin Razzokov, has signed a Memorandum of Understanding (MoU) with the Center for Advanced Technologies (CAT) under the Ministry of Higher Education, Science and Innovation, represented by its deputy Director, Dr. Dilbar Dalimova.
This MoU marks the beginning of a collaborative partnership aimed at advancing research in several critical areas, including:
- Plasma Medicine: Leveraging non-thermal plasma (NTP) for cancer treatment through a combination of computer simulations and experimental studies to understand its selective effects on cancer cells.
- Neurological Diseases: Addressing the complexities of diseases such as Parkinson's and Alzheimer's by exploring the impact of electric fields and drugs on amyloid fibers using a blend of in-vitro experiments and computer simulations.
- Artificial Intelligence: Utilizing AI to identify peptide-based inhibitors for proteins involved in various diseases.
- Chronic Wound Healing: Investigating the potential of NTP to accelerate wound healing through combined in-vivo and in-silico studies.
Both IFAR and CAT are committed to sharing resources, expertise, and information to achieve these objectives, with plans for regular meetings, joint publications, and presentations at scientific conferences. This collaboration aims to develop innovative solutions and standards for medical treatments, benefiting the scientific community and patients alike.
We look forward to the groundbreaking research and advancements that will emerge from this partnership over the next five years.
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