The Bypass
Placing a crafted NTUSER.MAN in C:\Users\<target>\ loads persistence keys into HKCU on next logon. The hive is loaded directly from disk without invoking registry APIs.

CmRegisterCallbackEx monitors registry operations. Hive loads are not registry operations. The callbacks are not invoked.

Filesystem events will trigger. Writing the file to the profile directory is visible to any EDR monitoring file operations. Registry-focused detections remain blind.