📚در مطالعه چاپ شده در مجله Brain Stimulation (ضریب تاثیر=5) 49 بیمار اسکیزوفرنی در دو گروه، تحریک واقعی و ساختگی را همراه با آموزش شناختی دریافت کردند. بهبود معناداری در تکلیف حافظه کاری تمرین شده و نیز در تعمیم به سایر تکالیف توجه و گوشبهزنگی دیده شد. این اولین مطالعهای است که اثرات بلندمدت معناداری از tDCS را در اسکیزوفرنی نشان میدهد. با توجه به درمانهای نه چندان موثر حال حاضر، تحریک الکتریکی مغز میتواند به روش مهمی در اصلاح مشکلات شناختی افراد دارای اسکیزوفرنی تبدیل گردد.
📚Stimulating cognition in schizophrenia: A controlled pilot study of the effects of prefrontal transcranial direct current stimulation upon memory and learning
⚪️Brain Stimulation
⭕️ Background: Schizophrenia is characterized by prominent cognitive deficits, impacting on memory and learning; these are strongly associated with the prefrontal cortex.
⭕️ Objective/hypothesis: To combine two interventions, transcranial direct current stimulation (tDCS) over the prefrontal cortex and cognitive training, to examine change in cognitive performance in patients with schizophrenia.
⭕️ Methods: A double blind, sham-controlled pilot study of 49 patients with schizophrenia, randomized into real or sham tDCS stimulation groups. Subjects participated in 4 days of cognitive training (days 1, 2, 14, 56) with tDCS applied at day-1 and day-14. The primary outcome measure was change in accuracy on working memory and implicit learning tasks from baseline. The secondary outcome measure was the generalization of learning to non-trained task, indexed by the CogState neuropsychological battery. Data analysis was conducted using multilevel modelling and multiple regressions.
⭕️ Results: 24 participants were randomized to real tDCS and 25 to sham. The working memory task demonstrated a significant mean difference in performance in the tDCS treatment group: at day-2 (b = 0.68, CI 0.14–1.21; p = 0.044) and at day-56 (b = 0.71, 0.16–1.26; p = 0.044). There were no significant effects of tDCS on implicit learning. Trend evidence of generalization onto untrained tasks of attention and vigilance task (b = 0.40, 0.43–0.77; p = 0.058) was found.
⭕️ Conclusions: This is the first study to show a significant longer-term effect of tDCS on working memory in schizophrenia. Given the current lack of effective therapies for cognitive deficits, tDCS may offer an important novel approach to modulating brain networks to ameliorate cognitive deficits in schizophrenia.
https://goo.gl/Zb0y2y
(Shared by Ms. M. Imani)
📚Stimulating cognition in schizophrenia: A controlled pilot study of the effects of prefrontal transcranial direct current stimulation upon memory and learning
⚪️Brain Stimulation
⭕️ Background: Schizophrenia is characterized by prominent cognitive deficits, impacting on memory and learning; these are strongly associated with the prefrontal cortex.
⭕️ Objective/hypothesis: To combine two interventions, transcranial direct current stimulation (tDCS) over the prefrontal cortex and cognitive training, to examine change in cognitive performance in patients with schizophrenia.
⭕️ Methods: A double blind, sham-controlled pilot study of 49 patients with schizophrenia, randomized into real or sham tDCS stimulation groups. Subjects participated in 4 days of cognitive training (days 1, 2, 14, 56) with tDCS applied at day-1 and day-14. The primary outcome measure was change in accuracy on working memory and implicit learning tasks from baseline. The secondary outcome measure was the generalization of learning to non-trained task, indexed by the CogState neuropsychological battery. Data analysis was conducted using multilevel modelling and multiple regressions.
⭕️ Results: 24 participants were randomized to real tDCS and 25 to sham. The working memory task demonstrated a significant mean difference in performance in the tDCS treatment group: at day-2 (b = 0.68, CI 0.14–1.21; p = 0.044) and at day-56 (b = 0.71, 0.16–1.26; p = 0.044). There were no significant effects of tDCS on implicit learning. Trend evidence of generalization onto untrained tasks of attention and vigilance task (b = 0.40, 0.43–0.77; p = 0.058) was found.
⭕️ Conclusions: This is the first study to show a significant longer-term effect of tDCS on working memory in schizophrenia. Given the current lack of effective therapies for cognitive deficits, tDCS may offer an important novel approach to modulating brain networks to ameliorate cognitive deficits in schizophrenia.
https://goo.gl/Zb0y2y
(Shared by Ms. M. Imani)
با تلاش محققان دانشگاه علوم پزشکی شیراز نخستین مقاله از ایران در معتبرترین مجله تخصصی «خواب» منتشر شد
نخستین مقاله محققان از ایران در معتبرترین مجله تخصصی «خواب و اختلالات خواب» با عنوان
The impact of chronic sleep restriction on neuronal number and volumetric correlates of the dorsal respiratory nuclei in a rat model
در مجله SLEEPاز انتشارات Oxfordبا ضریب تاثیر پنج ساله 5.753 منتشر شد.🌺🔽
نخستین مقاله محققان از ایران در معتبرترین مجله تخصصی «خواب و اختلالات خواب» با عنوان
The impact of chronic sleep restriction on neuronal number and volumetric correlates of the dorsal respiratory nuclei in a rat model
در مجله SLEEPاز انتشارات Oxfordبا ضریب تاثیر پنج ساله 5.753 منتشر شد.🌺🔽
كارگاه رديابي چشم Eye Tracking
تهران
22 ارديبهشت
مركز مشاوره دانشگاه تهران
02188503633 داخلي 210
https://goo.gl/bA3W3F
تهران
22 ارديبهشت
مركز مشاوره دانشگاه تهران
02188503633 داخلي 210
https://goo.gl/bA3W3F
🔼 Yet another new publication contributed by NSL, Dept. of Neuroscience. And our further reports are still ahead🌺
ضمن تبریک به پژوهشگران و همکاران و اساتید علوم اعصاب، با مسرت به اطلاع همگی اعضای محترم میرساند دسترسی آنلاین به معتبرترین پلتفرم و دیتابیس ارزیابی برخط کارکردهای عصب شناختی انگلستان CBS به صورت نامحدود از امروز در NSL فراهم شده است. 🌺🌺🌺
🔼یکی دیگر مقالات با پیام مهم در حوزه ترجمان دانش مغز و اعصاب که با همکاری مرکز تحقیقات استریولوژی و هستوموفولوژی، و گروه علوم اعصاب در ژورنال معتبر EXCLI اخیرا منتشر شده است. تبریک صمیمانه به اساتید و همکاران جدی و پرتلاش🌺🌺
Thanks to all for attending this. Below is the outline of our braimstormed ideas. Will do it! ⬇️