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The six cellular pathways to longevity are the same pathways to chronic metabolic disease:

Glycation
Oxidative stress
inflammation
Mitochondrial dysfunction
Insulin resistance
Membrane instability

And none of these pathways are druggable, except maybe inflammation, and that may be downstream of the other five.
~ Robert H Lustig MD

Research February 11, 2021
Response to Cancer Immunotherapy May Be Affected by Genes We Carry from Birth 
By Laura Kurtzman

A scanning electron micrograph of an oral squamous cancer cell (white) being attacked by two cytotoxic T cells (red), part of a natural immune response. Image by NIH

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors canno accurately predict which of their patients will respond.  
A new study finds that inherited genetic variation plays a role in who is likely to benefit from checkpoint inhibitors, which release the immune system’s brakes so it can attack cancer. The study also points to potential new targets that could help even more patients unleash their immune system’s natural power to fight off malignant cells. 

People who respond best to immunotherapy tend to have “inflamed” tumors that have been infiltrated by immune cells that are capable of killing both viruses and cancer. This inflammation is also driven by the immune signaling molecule interferon. 

“There are some factors that are already associated with how well the immune system responds to tumors,” said Elad Ziv, MD, professor of medicine at UCSF and co-senior author of the paper, published Feb. 9, 2021, by an international team in Immunity. “But what’s been less studied is how well your genetic background predicts your immune system’s response to the cancer. That’s what is being filled in by this work: How much is the immune response to cancer affected by your inherited genetic variation?” 

Up to 20 Percent of Variation Based on Genes 
The study suggests that, for a range of important immune functions, as much as 20 percent of the variation in how different people’s immune systems are able to attack cancer is due to the kind of genes they were born with, which are known as germline genetic variations.   

That is a significant effect, similar to the size of the genetic contribution to traits like high blood sugar levels or obesity."

Pharma phun with blood-altering drugs started long before COnVID. Before the fraudulent mess of corona broke out, I was deep into root causes of cardiovascular illness and related genetics and saved this YouTube by Ivor
Cummins to my favorites!

A simplified list of functional genes (enzymes) and what they do ... these are all found in chaga mushrooms, a helpful fungus esp. if you have variants in SOD, CAT, GSH, CYP450 genes.

(a) Enzymes that prevent oxidative stress:
Superoxide dismutase
b) Enzymes that prevent cellular growth:
Protease, Glucoamylase
c) Enzymes that promote detoxification:
Peroxidase, Cytochrome P-450

"Are we headed for the situation where the ~30% unvaxxed will be devoting their lives to operating whatever is left of the economic infrastructure and serving as caretakers for the vaxxed?

I realize the above sounds extreme, and maybe when more data are gathered from myriad credible sources the results and conclusions may change, but right now the above data seem to synchronize with the demonstrated underlying mechanisms of damage.  Additionally, we seem to be doubling down on inoculations, with fourth booster being proposed for Israel, and UK suggesting quarterly boosters.

The conclusion (if supported by further data) is that essentially EVERY inoculant recipient suffers damage, with more damage after each shot.  Given the seriousness of the types of damage (autoimmune diseases, cancer, re-emergent dormant infections, clotting/strokes, cardiac damage, etc.), these effects will translate into lifespan reduction, which should be counted as deaths from the inoculations.  So, in the USA, where ~200M people have been fully inoculated, the number of deaths will not be the 10,000 or so reported in VAERS, or the 150,000+ scaled-up deaths from VAERS, but could be closer to tens of millions when the inoculation effects play out".

https://stevekirsch.substack.com/p/bhakdiburkhardt-pathology-results

👇👇👇👇👇👇👇👇👇👇👇👇
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I'm listening to Dr. Joseph Mercola - Take Control of Your Health | How to Break Free of Fear Addiction Discussion Between Dr. Mark McDonald & Dr. Mercola on Podbean, check it out! https://www.podbean.com/ea/dir-ggg26-11f57465

Fear paralyzes rational thinking ... perpetual trauma keeps some people from using their minds. Ambivalence and curiosity are necessary for challenging government propaganda.

Our limbic system functions in two modes: safety and danger. Governmnent propaganda would have us believe that our safety can only be found via government. That sets the stage for the fraud called COVID.

The stress of fear, danger, is massively destructive to our health.

I'm listening to Informed Dissent on Podbean, check it out! https://www.podbean.com/pa/dir-wcd7e-214196

The intersection of health care and politics..